Independent register of U.S. FDA drug recalls · updated Oct 10, 2026
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Cross-contamination

Traces of another drug - most often penicillin - got into the product from shared equipment or facilities. Even trace penicillin can trigger a severe allergic reaction in someone who was never meant to receive it.

782 FDA drug recalls with this cause, newest first.

Cross-contamination means a product picked up traces of a different drug during manufacturing, repackaging or handling - usually because equipment or a facility was shared. Penicillin is the classic case: it is a potent allergen, so FDA requires it to be made in fully separate facilities, and a single lapse can put every product that passed through the same line on the recall list. Most of these recalls are precautionary sweeps of everything a firm handled during the affected period, which is why one event can add hundreds of entries at once.

Class II · Moderate risk

Necon 1/35-28

Cross Contamination With Other Products: The firm recalled Zovia, Lutera, Necon, and Zenchent, because certain lots could potentially be contaminated with trace amounts of Hydrochlorothiazide (HCTZ).

Terminated Cross-contamination Watson Laboratories Inc NDC 52544-552-28 D-017-2013
Class II · Moderate risk

Necon 10/11

Cross Contamination With Other Products: The firm recalled Zovia, Lutera, Necon, and Zenchent, because certain lots could potentially be contaminated with trace amounts of Hydrochlorothiazide (HCTZ).

Terminated Cross-contamination Watson Laboratories Inc NDC 52544-554-28 D-016-2013
Class II · Moderate risk

Zenchent (norethindrone and ethinyl estradiol)

Cross Contamination With Other Products: The firm recalled Zovia, Lutera, Necon, and Zenchent, because certain lots could potentially be contaminated with trace amounts of Hydrochlorothiazide (HCTZ).

Terminated Cross-contamination Watson Laboratories Inc NDC 52544-953-28 D-015-2013
Class II · Moderate risk

Lutera (levonorgestrel and ethinyl estradiol)

Cross Contamination With Other Products: The firm recalled Zovia, Lutera, Necon, and Zenchent, because certain lots could potentially be contaminated with trace amounts of Hydrochlorothiazide (HCTZ).

Terminated Cross-contamination Watson Laboratories Inc NDC 52544-949-28 D-014-2013
Class II · Moderate risk

Zovia (ethynodiol diacetate and ethinyl estradiol)

Cross Contamination With Other Products: The firm recalled Zovia, Lutera, Necon, and Zenchent, because certain lots could potentially be contaminated with trace amounts of Hydrochlorothiazide (HCTZ).

Terminated Cross-contamination Watson Laboratories Inc NDC 52544-383-28 D-013-2013
Class II · Moderate risk

Doxazosin Tablets

Cross Contamination w/Other Products: During stability testing chromatographic review revealed extraneous peaks identified as acetaminophen and codeine.

Terminated Cross-contamination Mylan Pharmaceuticals Inc. D-033-2013
Class II · Moderate risk

Estradiol Hemihydrate M20 EP/USP Powder

Cross Contamination w/Other Products: This active pharmaceutical ingredient is being recalled due to cross contamination with another product.

Terminated Cross-contamination Bayer HealthCare Pharmaceuticals Inc. D-1433-2012